- Mitochondrial disease is a rare disorder that affects the cells' ability to produce energy. There is no cure for mitochondrial disease123. The treatment is mainly supportive and may include nutritional management, exercise, and/or vitamin or amino acid supplements12. Some small molecules, such as idebenone and omaveloxolone, are approved for specific types of mitochondrial diseases, such as LHON and Friedreich’s ataxia3. Avoiding stress may also help reduce symptoms1.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.There is no cure for mitochondrial disease. Certain supplements—thiamine (B1), riboflavin (B12), vitamin C, vitamin E, Lipoic acid, and coenzyme Q10 —may help treat certain aspects of the disease. Avoiding stress may also help reduce symptoms.www.verywellhealth.com/mitochondrial-disease-28…Treatment for mitochondrial disease Currently there is no highly effective treatment or cure for mitochondrial disorder. The management of mitochondrial disease is supportive therapy, which may include nutritional management, exercise and/or vitamin or amino acid supplements.www.chop.edu/conditions-diseases/mitochondrial-d…As for most rare diseases, there are practically no treatments available in the clinic for mitochondrial diseases. Idebenone, a small molecule, is approved for the treatment of Leber hereditary optic neuropathy (LHON), and omaveloxolone, another small molecule, is approved for the treatment of Friedreich’s ataxia.www.nature.com/articles/d41573-023-00067-z
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Mitochondrial Diseases: Causes, Symptoms & Treatment
How is a mitochondrial disease treated? Treatment for a mitochondrial disease varies based on the type and your symptoms. Treatment could include: Taking medications to reduce symptoms, like medications to prevent seizures. Taking vitamins or supplements, like riboflavin, coenzyme Q10 and carnitine. … See more
Symptoms of mitochondrial diseases vary based on the type and location of the affected cells. They can range from mild to severe and could … See more
A lack of energy production from mitochondria in your cells causes mitochondrial disease. Mitochondria are responsible for … See more
Mitochondrial diseases affect how your organs function. It can cause the following complications: 1. Increased risk of infection. 2. Strokes. 3. Pancreatic failure. 4. Parathyroidfailure. 5. Diabetes. 6. Liver failure. 7. Cardiomyopathy. 8. Kidney disease. 9. Dementia. 10. Gastrointestinal conditions. 11. Drooping eyelid (ptosis). … See more
Current and Emerging Clinical Treatment in Mitochondrial Disease
WEBMar 1, 2021 · Acipimox, bezafibrate, omaveloxolone and REN001 aim to treat mitochondrial disease by increasing the cellular mitochondrial concentration. In …
- Author: Rory J Tinker, Albert Z Lim, Renae J Stefanetti, Robert McFarland, Robert McFarland
- DOI: 10.1007/s40291-020-00510-6
- Publish Year: 2021
- Publication: Mol Diagn Ther. 2021; 25(2): 181-206.
A Modern Approach to the Treatment of Mitochondrial Disease
WEBAside from symptom-based management, treatment of mitochon-drial disease focuses on maintaining optimal health, using preventive measures to mitigate symptom worsening …
Mitochondrial disease in adults: recent advances and …
WEBWhile the current management strategy for mitochondrial disease focuses on surveillance for multisystem involvement and effective symptomatic treatment, new endeavours are underway to find better treatments, …
Mitochondrial Disorders | National Institute of Neurological …
WEBFeb 28, 2024 · There are currently no cures or specific treatments for mitochondrial disorders. Generally, treatment is focused on managing symptoms and may include …
Mitochondrial Disease Symptoms and Treatment
WEBOct 27, 2021 · Mitochondrial disease is a genetic condition that affects the energy production of cells. It can cause various symptoms in different organs and has no cure. Learn about the diagnosis, treatment options, …
Mitochondrial Disease Clinic - Clinical Genomics - Mayo Clinic
WEBMayo Clinic offers specialized care and genetic counseling for patients with mitochondrial disease, a group of disorders that affect energy production in cells. Learn about the …
Mitochondrial Disease: Advances in clinical diagnosis, …
WEBPrimary mitochondrial disease encompasses an impressive range of inherited energy deficiency disorders having highly variable molecular etiologies as well as clinical onset, …
Diagnosis and management of mitochondrial disease: a consensus …
WEBDec 11, 2014 · 302 Citations. 46 Altmetric. Metrics. Abstract. Purpose: The purpose of this statement is to review the literature regarding mitochondrial disease and to provide …
Mitochondrial Diseases: Hope for the Future: Cell
WEBMar 26, 2020 · Treatments for mitochondrial diseases are currently focused on symptomatic management rather than improving the biochemical defect caused by a …
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