The region around Chillicothe was the center of the ancient Hopewell tradition, which flourished from 200 BC until 500 AD. This Amerindian culture had trade routes extending to the Rocky Mountains. They built … See more

Chillicothe lies within the ecoregion of the Western Allegheny Plateau. It lies between the Scioto River and Paint Creek near their confluence.
According to the United States Census Bureau, … See more

As the only city in the area, Chillicothe is a hub for economic activity. Malls, hospitals, prisons and a college campus are among the largest employers. One of the most visible is the Pixelle paper mill, formerly known as … See more