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  1. Peyronie disease - Symptoms and causes - Mayo Clinic

    • Peyronie disease is a condition that causes scar tissue and curvature in the penis, leading to pain and erectile problems. Learn about the symptoms, possible causes, risk factors, complications and t… See more

    Overview

    Peyronie (pay-roe-NEE) disease is a condition in which fibrous scar tissue forms in the deeper tissues under the skin of the penis. This causes curved, painful erections. I… See more

    Mayo Clinic
    Symptoms

    Peyronie disease symptoms might start suddenly or appear over time. The most common … See more

    Mayo Clinic
    Causes

    The exact cause of Peyronie disease isn't clear. But various factors seem to be involved. It's thought Peyronie disease most often results from repeated injury to the penis d… See more

    Mayo Clinic
    Risk Factors

    Minor injury to the penis doesn't always lead to Peyronie disease. Various factors can contribute to poor wound healing and scar tissue buildup that might play a role in Peyronie di… See more

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    Complications

    Peyronie disease might lead to troubles that include: 1. Not being able to have sex. 2. Trouble getting or keeping an erection, also called erectile dysfunction. 3. Anxiety, stress, or d… See more

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    However, most of the time it requires medical treatment. Treatment options for Peyronie’s disease include injections, medical therapies, and surgery. Injections are often used to treat the acute phase of Peyronie’s disease. Known as intralesional injections, this treatment can be injected directly into the plaques.
    Men whose sexual or nonsexual activities (such as sports) cause micro-injuries to the penis are more likely to develop Peyronie’s disease. If you have certain connective tissue or autoimmune disorders, you may have a higher chance of developing Peyronie’s disease.
    Peyronie’s (pay-roe-NEEZ) disease is a condition in which scar tissue (plaque) in your penis causes it to bend, curve or lose length or girth (circumference). You may be able to feel the scar tissue through your skin, or you may have pain in a specific part of your penis as the scar tissue forms.
    There is an association with other connective tissue disorders, specifically Dupuytren’s contracture, affecting the palms of the hands. The most popular theory today is that Peyronie's disease is induced by trauma.