Abemaciclib: Uses, Dosage, Side Effects, Warnings - Drugs.com
WebJun 2, 2023 · Abemaciclib works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells. Abemaciclib is used in combination with an aromatase inhibitor such as anastrozole (Arimidex), exemestane (Aromasin), or letrozole (Femara) to treat a certain type of hormone receptor ...
Abemaciclib - Wikipedia
WebAbemaciclib, sold under the brand name Verzenio among others, is a medication for the treatment of advanced or metastatic breast cancers. It was developed by Eli Lilly and it acts as a CDK inhibitor selective for CDK4 and CDK6. It was designated as a breakthrough therapy for breast cancer by the US Food and Drug Administration (FDA) in October ...
Abemaciclib (Oral Route) Description and Brand Names - Mayo Clinic
WebApr 1, 2024 · Descriptions. Abemaciclib is used together with tamoxifen or an aromatase inhibitor (eg, anastrozole, exemestane, letrozole) to treat hormone receptor (HR)-positive, HER-2 negative, node-positive, early breast cancer with a high risk of coming back as determined by your doctor.
abemaciclib oral: Uses, Side Effects, Interactions, Pictures ... - WebMD
WebGeneric Name: abemaciclib. This medication is used to treat certain types of breast cancer. Abemaciclib works by slowing or stopping the growth of cancer cells. It belongs to a class of drugs...
Abemaciclib - NCI - National Cancer Institute
WebAbemaciclib is approved to treat: Breast cancer that is hormone receptor positive (HR+) and HER2 negative (HER2-). It is used: In adults whose cancer has spread. It is used: With fulvestrant in adults whose cancer got worse after treatment with hormone therapy.
Abemaciclib (Verzenios) | Breast Cancer Now
Web1. What is abemaciclib? Abemaciclib is a targeted or biological therapy drug. When used to treat breast cancer, abemaciclib is taken alongside hormone (endocrine) therapy. Abemaciclib is the drug’s non-branded name. Its brand name is Verzenios. It belongs to a group of drugs called CDK (cyclin dependent kinase) inhibitors.
Abemaciclib (Verzenios®) | Macmillan Cancer Support
WebAbout our information. How we can help. What is abemaciclib (Verzenios®)? Abemaciclib (Verzenios®) belongs to a group of targeted therapy drugs called cancer growth inhibitors. It is best to read our information about abemaciclib with our general information about the type of cancer you have.
Abemaciclib: MedlinePlus Drug Information
WebAbemaciclib is used in combination with tamoxifen (Soltamox) or an aromatase inhibitor such as anastrozole (Arimidex), exemestane (Aromasin), or letrozole (Femara) to treat a certain type of hormone receptor-positive, early breast cancer.
Abemaciclib: Uses, Interactions, Mechanism of Action - DrugBank …
WebDrugBank Accession Number. DB12001. Background. Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market …
Impact of dose reductions on adjuvant abemaciclib efficacy for
Web2 days ago · In monarchE, adjuvant abemaciclib significantly improved invasive disease-free survival (IDFS) and distant relapse-free survival (DRFS), with sustained benefit beyond the 2-year treatment period.
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