α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, better known as AMPA, is a compound that is a specific agonist for the AMPA receptor, where it mimics ...
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The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor is an ionotropic transmembrane receptor for glutamate (iGluR) and predominantly Na+ ion ...
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AMPA
Compounds
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α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, better known as AMPA, is a compound that is a specific agonist for the AMPA receptor, where it mimics the effects of the neurotransmitter glutamate. Wikipedia
Molar mass: 186.17 g/mol
3D model (JSmol): Interactive image
Jan 31, 2022 · Glutamatergic α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) are central to regulate excitatory synaptic transmission ...
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AMPA ((±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid); solid; Potent excitatory amino acid that interacts selectively with central AMPA/kainate ...
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The AMPA receptor agonist (R,S)-AMPA is typically used at concentrations of 1-100 µM. At 10 µM, (R,S)-AMPA from Hello Bio induces a large depolarising current.
Changes in AMPAR number and/or function are a core feature of synaptic plasticity and age-related cognitive decline, AMPARs are highly dynamic proteins that are ...
α-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors are glutamate-gated channels that mediate most of the fast excitatory synaptic ...
AMPA receptors are glutamate-gated ion channels, present in a wide range of neuron types and in glial cells. Their main role is to mediate fast excitatory ...