Manisa Province (Turkish: Manisa ili) is a province and metropolitan municipality in western Turkey. Its area is 13,339 km 2, and its population is 1,468,279 (2022). Its neighboring provinces are İzmir to the west, Aydın to the south, Denizli to the southeast, Uşak to the east, Kütahya to the northeast, and Balıkesir to the north.

Manisa, city, western Turkey. It lies in the valley of the Gediz River (ancient Hermus River), below Mount Sipylus (Manisa Dağı), 20 miles (32 km) northeast of İzmir. It was called Magnesia ad Sipylum in ancient times, and the Magnetes of Thessaly are thought to have been its first inhabitants, in the 12th century bce.