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  1. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK544287

    Pioglitazone - StatPearls - NCBI Bookshelf

    WebJul 4, 2023 · Administration. Pioglitazone is taken orally, with or without food. It can be taken as monotherapy but is usually used as an adjunct …

    • Published: 2023/07/04

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    Pioglitazone: mechanism of action - PubMed
    pubmed.ncbi.nlm.nih.gov
    Do We Still Need Pioglitazone for the Treatment of Type 2 …
    diabetesjournals.org
    Pioglitazone Dosage Guide + Max Dose, Adjustments - …
    drugs.com
    Metformin and pioglitazone Uses, Side Effects & Warnings …
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    Pioglitazone (Oral Route) Side Effects - Mayo Clinic
    mayoclinic.org
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  2. Mayo Clinic
    https://www.mayoclinic.org/drugs-supplements/...

    Pioglitazone (Oral Route) Description and Brand Names - Mayo …

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    Pioglitazone Side Effects: Common, Severe, Long Term
    drugs.com
    Pioglitazone Oral: Uses, Side Effects, Interactions, Pictures …
    webmd.com
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  3. Mayo Clinic
    https://www.mayoclinic.org/drugs-supplements/...

    Pioglitazone (Oral Route) Proper Use - Mayo Clinic

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    Actos (pioglitazone) dosing, indications, interactions, …
    reference.medscape.com
    How and when to take pioglitazone - NHS
    nhs.uk
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  4. Pioglitazone

    Common brand names: Actos
    Interactions

    Product interactions for this drug/drug-class include:

    • Pioglitazone (> 15 mg) with Strong CYP2C8 Inhibitors (Contraindicated)
    • Pioglitazone (<=15mg); Rosiglitazone with Strong CYP2C8 Inhibitor (Severe Interaction)
    • Antidiabetic Agents with Gymnema (Severe Interaction)
    • Antidiabetic Agents with Gatifloxacin (Severe Interaction)
    • Pioglitazone; Repaglinide with Abiraterone (Severe Interaction)
    • Zuranolone with CYP3A4 Inducers (Severe Interaction)

    Before taking this medication, tell your doctor if you've had:

    • Heart disease (such as congestive heart failure, chest pain)
    • Liver disease
    • Fluid in your lungs
    • Swelling (edema)
    • Anemia
    • A certain eye problem (macular edema)
    • Bladder cancer

    Warnings

    • If you drink alcohol, discuss the safe use of alcohol while using this medication with your healthcare professional. ;

    For informational purposes only. Consult a medical professional for advice.

    Source: First Databank Learn more

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  5. People also ask
    What is pioglitazone used for?
    Pioglitazone is an oral antidiabetic from the thiazolidinedione drug class, FDA approved for treating type 2 diabetes mellitus in adults, as an adjunct to diet and exercise. Maintaining blood glucose levels as close to normal as possible is the main goal in diabetes management to prevent the complications of type 2 diabetes mellitus.

    Pioglitazone - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    Does pioglitazone reduce glycemic control?
    Pioglitazone can decrease hemoglobinA1C by 0.5 and 1.4 percent when used as monotherapy. The magnitude of benefit on glycemic control is variable with combination therapy with other antidiabetics, including insulin. For adults, the dose starts initially at 15 mg or 30 mg orally once daily.

    Pioglitazone - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    How do you take pioglitazone?
    Pioglitazone comes as a tablet to take by mouth. It is usually taken once daily with or without meals. Take pioglitazone at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take pioglitazone exactly as directed.

    Pioglitazone: MedlinePlus Drug Information

    medlineplus.gov
    What are the contraindications to pioglitazone?
    Contraindications to the use of pioglitazone include the following scenarios : Diabetic ketoacidosis or type 1 diabetes, since pioglitazone is active only in the presence of insulin. The Beers Criteria lists pioglitazone as a potentially inappropriate medication (PIM) for the geriatric population with heart or kidney failure.

    Pioglitazone - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
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  6. Medscape
    https://reference.medscape.com/drug/actos-pioglitazone-342726

    Actos (pioglitazone) dosing, indications, interactions, adverse …

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    Pioglitazone Interactions
    Actos Dosage
    Actos Pioglitazone Hcl 15 Mg
    +2
    Pioglitazone Medscape
    Pioglitazone Actos 30 Mg Tablet
  7. Drugs.com
    https://www.drugs.com/dosage/pioglitazone.html

    Pioglitazone Dosage Guide + Max Dose, Adjustments - Drugs.com

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    Low Dose Pioglitazone
    Actos Dose
    Heart Failure
    +2
    Max Dose Pioglitazone
    Pioglitazone Dose Range
  8. DrugBank Online
    https://go.drugbank.com/drugs/DB01132

    Pioglitazone: Uses, Interactions, Mechanism of Action

    WebPioglitazone metabolite M-III; Route of elimination. Approximately 15-30% of orally administered pioglitazone is recovered in the urine. The bulk of its elimination, then, is presumed to be through the excretion of unchanged …

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    Pioglitazone Interactions
    Pioglitazone Mechanism
  9. Drugs.com
    https://www.drugs.com/monograph/pioglitazone.html

    Pioglitazone Monograph for Professionals - Drugs.com

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    Diabetes Medicine Pioglitazone
    Pioglitazone Ncbi
    +3
    Type 2 Diabetes Mellitus
    Nyha Class Iii Antidiabetic Drugs
    Pioglitazone Med Guide
  10. MedlinePlus
    https://medlineplus.gov/druginfo/meds/a699016.html

    Pioglitazone: MedlinePlus Drug Information

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    Pioglitazone Class
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  11. StatPearls
    https://www.statpearls.com/point-of-care/27238

    Pioglitazone | Treatment & Management | Point of Care - StatPearls

    Tags:
    Pioglitazone Class
    Type 2 Diabetes Mellitus
  12. Wikipedia
    https://en.wikipedia.org/wiki/Pioglitazone

    Pioglitazone - Wikipedia

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    liver (CYP2C8)
    AU: B3
    Actos, others
    Actos Pioglitazone